Description
MK-677 (Ibutamoren) Overview – EliteBiogenix.com
MK-677, also known as Ibutamoren, Nutrobal, or Oratrope, is a potent ghrelin receptor agonist and growth hormone secretagogue. With a molecular weight of 528.662, MK-677 stimulates the pituitary gland to release human growth hormone (HGH) and is often grouped with selective androgen receptor modulators (SARMs). Unlike ghrelin, MK-677 is not a peptide but a spiropiperidine compound. Its ability to cross the blood-brain barrier allows it to function as a neuropeptide within the central nervous system, making it a unique and powerful compound.
How MK-677 Stands Out Among Growth Hormone Secretagogues
MK-677 is a highly effective growth hormone stimulant, often found alongside SARMs in research catalogs. Unlike other compounds like GHRP-6 and GHRP-2, MK-677 elevates insulin-like growth factor 1 (IGF-1) levels for up to 24 hours after a single dose without disrupting the body’s natural pulsatile GH release. Since it does not interact with androgen receptors, MK-677 may improve body composition without negatively affecting testosterone or other endogenous androgens. Research also suggests that MK-677 may work synergistically with growth hormone-releasing peptides such as Tesamorelin and Ipamorelin, enhancing its potential benefits.
How MK-677 Works
MK-677 mimics the action of ghrelin, the hunger hormone, to stimulate the release of growth hormone and IGF-1. Unlike many growth hormone peptides, MK-677 is orally bioavailable, eliminating the need for injections. This makes it a convenient option for researchers. At EliteBiogenix.com, we offer premium MK-677 with verified purity, fast shipping, secure payment processing, and exceptional customer support, making us the trusted source for high-quality research compounds.
Clinically Researched Benefits of MK-677
Extensive studies have demonstrated the potential benefits of MK-677, including:
- Increased growth hormone and IGF-1 levels
- Enhanced muscle mass and lean body composition
- Reduced body fat
- Improved bone density
- Accelerated muscle recovery and growth
- Strengthened immune function
- Better REM sleep quality
- Increased appetite
- Reversal of growth hormone deficiency
- Potential neuroprotective effects against beta-amyloid buildup
Key Findings from MK-677 Studies
- Growth Hormone Release: Research shows that MK-677 significantly increases IGF-1 and IGF-binding protein-3 (IGFBP-3) levels, making it a promising option for addressing growth hormone deficiencies and supporting muscle growth.
- Body Composition: Clinical trials have found that MK-677 improves bone mineral density, muscle mass, and overall body composition in older adults. A randomized controlled trial also noted enhanced nitrogen retention, even during calorie restriction, suggesting its potential for preserving muscle mass in challenging conditions.
- Sleep Quality: Studies indicate that MK-677 improves REM sleep duration and reduces REM latency, particularly in older adults. Enhanced stage 4 sleep, crucial for tissue repair, further highlights its potential for recovery and neurological health.
- Chronic Disease Potential: Animal studies suggest that MK-677 may reduce neuroinflammation, neurodegeneration, and beta-amyloid buildup, offering potential preventive benefits against conditions like Alzheimer’s disease. However, more human studies are needed to confirm these findings.
Potential Side Effects of MK-677
While MK-677 shows promise, it is important to note that it is not FDA-approved for human consumption. Reported side effects include water retention, changes in blood pressure, and increased appetite due to its ghrelin-mimetic properties. Long-term use may also risk desensitizing ghrelin receptors. MK-677 is strictly for research purposes and should be handled with caution.
MK-677 Product Details
- CAS Number: 159752-10-0
- Chemical Formula: C27H36N4O5S
- Molar Mass: 528.662 g/mol
- Half-Life: 24 hours
- Class: Ghrelin Receptor Agonist, Growth Hormone Secretagogue
- Storage: Store in a cool, dry place away from direct sunlight to maintain stability.
Product Specifications:
- 30ml liquid MK-677 per bottle (25mg/ml concentration)
- Includes a graduated 1mL glass pipette for precise measurement
- UV-resistant glass bottle to minimize degradation
- Tamper-proof seal for safety
- Less than 5% concentration variance for consistency
- Formulated to prevent evaporation during storage
Disclaimer: MK-677 is a research chemical intended for laboratory use only. It is not approved for human consumption, dietary use, or as a sports supplement.
References:
- Oral administration of MK-677 increases markers of bone turnover in elderly adults. PubMed
- Design and biological activities of MK-677. PubMed
- MK-677 stimulates the GH/IGF-1 axis in GH-deficient adults. Journal of Clinical Endocrinology & Metabolism
- MK-677 improves sleep quality in humans. PubMed
- MK-677 reverses diet-induced catabolism. PubMed
- MK-677 alleviates amyloid-beta pathology in Alzheimer’s models. PubMed
Why Choose EliteBiogenix.com for MK-677?
At EliteBiogenix.com, we prioritize quality, safety, and customer satisfaction. Our MK-677 is rigorously tested for purity and consistency, ensuring reliable results for your research needs. With fast shipping, secure payment options, and dedicated support, we are your trusted partner in advanced research compounds.
Explore the potential of MK-677 today – exclusively at EliteBiogenix.com!
Disclaimer: This product is intended for research purposes only. It is not intended for human consumption, medical treatment, or therapeutic use without professional oversight.
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