Description
(18-35 year old demographic)
PT 141 Overview
PT 141, also referred to as Bremelanotide, is a cutting-edge peptide that primarily targets the Melanocortin 4 receptor (MC4-R) within the central nervous system, promoting sexual arousal. Research conducted on animal models has demonstrated that PT 141 effectively binds to MC4-R, enhancing sexual activity in both males and females. At EliteBioGenix, we provide high-quality PT 141 peptides for laboratory research, ensuring purity and reliability for scientific studies.
PT 141 for Sexual Health and Dysfunction
PT 141 shows significant potential as a therapeutic option for sexual disorders unrelated to blood flow issues. Unlike traditional erectile dysfunction treatments, PT 141 has been shown to induce erections in males who do not respond to conventional medications. Its unique mechanism of action makes it a promising candidate for addressing sexual dysfunction and improving overall sexual health.
Potential Medical Applications of PT 141
1. Hemorrhagic Shock and Enhanced Blood Flow
PT 141 is under investigation for its role in treating hemorrhagic shock. By binding to MC1-R and MC4-R receptors, it enhances blood supply to tissues, potentially preventing damage during reduced blood flow scenarios. Intravenous studies have shown minimal side effects, highlighting its safety profile.
2. Anti-Fungal and Anti-Inflammatory Properties
Recent animal studies suggest that MC1-R activation can combat fungal infections while reducing inflammation. Although further research is needed, this indicates PT 141’s potential as a novel treatment for fungal infections and inflammatory conditions, particularly in individuals with autoimmune diseases.
3. Cancer Prevention and Therapy
Variants of MC1-R have been linked to an increased risk of skin cancers, such as basal cell and squamous cell carcinoma. However, MC1-R also stimulates DNA repair pathways, offering potential applications in cancer prevention and treatment.
4. Weight Loss and Metabolic Benefits
PT 141, along with similar peptides like Melanotan II, activates MC4-R, which promotes satiety and reduces calorie intake. Animal studies indicate that PT 141 can boost energy expenditure and improve metabolic function, making it a potential aid in weight management. Clinical trials have shown that subjects administered PT 141 experienced significantly greater weight loss compared to placebo groups.
PT 141 Research Data
- CAS Number: 1607799-13-2
- Molecular Formula: C50H68N14O10
- Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
- Molar Mass: 1025.182 g/mol
- Half-Life: 2.7 hours
- Class: Cyclic Heptapeptide
Storage and Usage Instructions
- Store reconstituted PT 141 under refrigeration.
- Each vial contains a lyophilized sample with a minimum purity of 96% (including stabilizing agents).
- 10mg of PT 141 per vial.
- Diluent and laboratory supplies are not included.
Important Note:
This product is intended solely for in vitro laboratory research by qualified professionals. It is not approved by the FDA for human or animal consumption and should not be misbranded, misused, or mislabeled as a drug, food, supplement, or cosmetic.
References:
- Reduction in corpora lutea number in obese melanocortin-4-receptor-deficient mice. PubMed
- Evaluation of PT-141 safety and pharmacokinetics in healthy males and patients with inadequate response to Viagra. PubMed
- PT-141 induces penile erection via brain and spinal melanocortin receptors. PubMed
- Melanotan II enhances proceptive sexual behaviors in female rats. PubMed
- Bremelanotide as a salvage treatment for sildenafil failures. PubMed
- Anti-fungal and anti-inflammatory effects of melanocortin against Candida albicans. PubMed
- Skin cancer risks associated with MC1-R variants. PubMed
- Skin phototype and melanocortin receptor activity. PubMed
- Melanotan II and thermogenic capacity in mice. PubMed
- Bremelanotide’s effect on body weight in obese women. PubMed
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