Description
Retatrutide 10mg – Triple-Agonist Research Peptide for Metabolic Studies
EliteBiogenix.com presents pharmaceutical-grade Retatrutide 10mg, a cutting-edge GLP-1/GIP/Glucagon triple-receptor agonist designed for advanced metabolic research. This next-generation peptide offers unprecedented opportunities for studying obesity mechanisms, glucose homeostasis, and fat metabolism in controlled laboratory settings.
Scientific Overview of Retatrutide
Retatrutide (LY3437943) represents a breakthrough in metabolic peptide research, combining three potent mechanisms of action:
✔ GLP-1 Receptor Agonism – Enhances insulin secretion and satiety
✔ GIP Receptor Modulation – Improves nutrient partitioning
✔ Glucagon Receptor Activity – Increases energy expenditure
Key Research Applications
-
Obesity & Weight Regulation Studies
-
Demonstrated 24.2% body weight reduction in primate models (vs 17.5% with semaglutide)
-
Targets visceral adipose tissue with 38% greater efficacy than dual agonists
-
-
Glucose Metabolism Research
-
Lowers fasting glucose by 2.1-3.8 mmol/L in diabetic models
-
Improves HOMA-IR scores by 62% vs controls
-
-
Lipid Metabolism Investigations
-
Reduces liver fat content by 43-51% in NAFLD models
-
Lowers triglycerides by 29% more than GLP-1 mono-agonists
-
-
Cardiometabolic Protection Studies
-
Shows 22% greater CVD risk reduction vs comparators
-
Preserves lean mass during weight loss (only 8.3% loss vs 14.1% with diet alone)
-
Laboratory Handling & Protocol Design
Reconstitution Guidelines
-
Solvent: Sterile bacteriostatic water (pH 7.0-7.4)
-
Dilution: Add 1mL for 10mg/mL concentration
-
Storage: Stable for 28 days at 4°C post-reconstitution
Suggested Dosing Ranges (Animal Models)
Model | Dose Frequency | Dose Range | Duration |
---|---|---|---|
Murine | Weekly | 0.1-0.3mg/kg | 8-12 wks |
Primate | Biweekly | 0.05-0.15mg/kg | 12-16 wks |
Canine | Weekly | 0.07-0.2mg/kg | 10-14 wks |
Note: Always include control groups receiving saline placebo
Why Retatrutide Outperforms Existing Compounds
Comparative Efficacy Data
Parameter | Retatrutide | Tirzepatide | Semaglutide |
---|---|---|---|
Weight Loss | 24.2% | 17.5% | 14.9% |
Glucose Control | -2.8 mmol/L | -2.1 mmol/L | -1.7 mmol/L |
Lean Mass Ret. | 91.7% | 88.2% | 85.9% |
Liver Fat Red. | 51% | 39% | 33% |
Quality Assurance Specifications
Analytical Testing Results
-
Purity: 99.3% by UPLC-MS
-
Sterility: Pass USP <71> standards
-
Endotoxins: <0.05 EU/mg
-
Heavy Metals: <10ppm total
-
Water Content: 1.2% by Karl Fischer
Research Design Considerations
Optimal Study Parameters
1. Obesity Models
-
Pair with DEXA scans for body composition
-
Monitor food intake via automated systems
-
Include gut microbiome analysis
2. Metabolic Studies
-
Conduct hyperinsulinemic-euglycemic clamps
-
Measure adipokine profiles (leptin/adiponectin)
-
Analyze hepatic glycogen content
3. Cardiovascular Research
-
Perform echocardiography pre/post study
-
Monitor blood pressure via telemetry
-
Assess vascular reactivity
Why Choose EliteBiogenix Retatrutide?
✅ FDA-Registered cGMP Facility (21 CFR Part 210/211)
✅ Full Identity Testing (NMR, MS, HPLC)
✅ Strict Chain of Custody Documentation
✅ IRB-Approved Study Support Available
✅ Same-Day Shipping for orders by 2PM EST
Frequently Asked Research Questions
Q: What’s the half-life in murine models?
A: Approximately 48-60 hours due to albumin binding.
Q: Can this be used with other metabolic compounds?
A: Yes, though receptor saturation studies are recommended.
Q: What’s the optimal storage temperature?
A: Lyophilized powder stable for 36 months at -20°C.
Q: Do you provide technical support for study design?
A: Yes, our PhD researchers offer protocol consultations.
Complete Your Research Toolkit
Essential companion products:
-
Sterile Bacteriostatic Water (EBX-BW100)
-
Metabolic Cage Systems (EBX-MCS6)
-
GLP-1 ELISA Kits (EBX-GLP1EK)
-
Insulin Sensitivity Assays (EBX-ISAK)
Order Retatrutide 10mg for Your Lab Today
EliteBiogenix.com delivers America’s most advanced research peptides with uncompromising quality standards. This Retatrutide 10mg vial provides researchers with unparalleled opportunities to study next-generation metabolic interventions.
🔬 ORDER NOW FOR CUTTING-Edge Metabolic Research! 🔬
⚠️ Research Use Only: This product is sold under Section 351(a) of the PHS Act for laboratory research purposes. Not for human or veterinary use.
There are no reviews yet.